Curcumin is the active ingredient in turmeric. It is the main curcuminoid in curcuma longa (about 80%). It belongs to the curcuminoids (desmethoxycurcumin, bidesmethoxycurcumin, dihydrocurcumin). They give the yellow colour to the rhizome of the turmeric from which they are extracted.
A promising but unavailable asset
Curcumin is often recommended for its virtues. It has been the subject of numerous scientific studies and continues to fuel the hopes of researchers with spectacular results in vitro. The prospects of transposing the results to the body have been limited until now because of its very low bioavailability and the difficulty for manufacturers to extract it.
the limitations of ordinary processes
Its low bioavailability is related to its fat solubility. Less than 1% of Curcuminoids are assimilated by the body in their standard form. To counter this low assimilation due to the liposolubility of curcumin, the association with piperine (black pepper extract) is currently used. This increases intestinal permeability by creating micro-lesions serving as a gateway for curcuma, with the disadvantage of increasing non-selective permeability and the passage of other substances and toxins. Some studies have shown the appearance of food intolerances and allergies, among others. Nevertheless, these results must be weighted on a case-by-case basis given the considerable doses often involved in the studies cited (>40mg/d/kg in rodents). Beyond the reservations expressed and the hopes raised, piperine does not seem to us to increase bioavailability significantly enough in comparison with other strategies.
Encapsulation techniques are also used to increase bioavailability. These include the use of liposomes for their ability to solubilise hydrophobic components, but the improvements reported here are still too inconclusive.
the limitations of ordinary processes.
the pitfall of fat solubility
To meet these challenges, we pursued two objectives: to increase the total bioavailability of curcuminoids and to refine the processes allowing higher concentrations in a liquid form. Based on the experiments we conducted, the choice was made to use a dispersion of Curcuminoid nanoparticles supportedby hydrophilic agents that cause partial solubilisation.
Curcumine ω, Solubilisation and Nanodispersion
To counteract this poor uptake, we developed a form of curcumin that synthesises between nanodispersion and solubilisation. This results in facilitated intestinal transport and not in increased permeability with piperine. This passive transport is the route used in the case of encapsulated curcumin and which allows such an increase in bioavailability. However, unlike encapsulated forms, the water-soluble form of Curcumine ω avoids the use of surfactants, and any chemical additives. The new generation of Curcumine ω has also increased the concentration of curcumin with increased bioavailability from 50mg/100ml to 1200mg/100ml.
>> More: Curcumine ω Technical
jerome DEBESNE (confirmed customer) - –
My brother who lives in Ireland has been taking curcumin+phycocyanine+magnesium+omeg3 every day and in larger than normal doses on the advice of a friend for years to reduce the effects of his fibromyalgia...it has saved his life (he says so). Before, after mowing the lawn, he would stay in bed for a week. Now he goes surfing several times a week. Of course, he has small crises from time to time but nothing like what he had before. Jérôme
bezombesolivier (confirmed customer) - –
Very good quality product.
The joint pains have been reduced or even disappeared after a few weeks.
After stopping consumption our joint pain returned so we continue.
I recommend this product.
Luca BORRI (confirmed customer) - –
I have been consuming phycocyanin, spirulina and curcumin for a few years now and have been looking into these products for a few months. I have to say that the quality is very good, with more than reasonable prices for the duration and quality of the products. It helps me a lot to reduce fatigue, aches and pains and to give even more during my crossfit training, being able to combine classes and crossfit during the day without worries.